Fast Food Restaurant – illustrative photo

Fast Food RestaurantSan Antonio, TX

McDonald's – 4422 West Commerce Street, San Antonio

Open 24 hours

Directions Call

Illustrative photo

Opening hours

Open 24 hours

Weekly opening hours of McDonald's
Monday	Open 24 hours
Tuesday	Open 24 hours
Wednesday	Open 24 hours
Thursday	Open 24 hours
Friday	Open 24 hours
Saturday	Open 24 hours
Sunday	Open 24 hours

Local time in San Antonio: 1:29 AM (CDT). Holiday hours may differ – call (210) 438-5020 to confirm.

Location & directions

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4422 West Commerce Street
San Antonio, TX 78237

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About McDonald's

Located at 4422 West Commerce Street in San Antonio, Texas, McDonald's is a fast food restaurant. It is one of 1,584 places to eat and drink we list in San Antonio.

McDonald's is open 24 hours a day, 7 days a week.

Service options include takeout, drive-through, and dine-in. On the menu: burgers.

Phone: (210) 438-5020.

Quick facts

Category: Fast Food Restaurant · Burger
Address: 4422 West Commerce Street, San Antonio, TX 78237
Phone: (210) 438-5020
Hours: Open 24 hours a day, 7 days a week
Listing updated: September 2026 · Suggest an edit

Popular times (estimated)

6AM

9AM

12PM

3PM

6PM

9PM

Estimated from typical visit patterns for fast food restaurants and this venue’s opening hours – not live data.

Features & amenities

Service options

Takeout
Drive-through
Dine-in

Amenities

Wi-Fi

Reviews

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Frequently asked questions

What are McDonald's's opening hours?

Open 24 hours a day, 7 days a week. Monday: Open 24 hours; Tuesday: Open 24 hours; Wednesday: Open 24 hours; Thursday: Open 24 hours; Friday: Open 24 hours; Saturday: Open 24 hours; Sunday: Open 24 hours.

Is McDonald's open on Sunday?

Yes, McDonald's is open on Sundays: Open 24 hours.

Where is McDonald's located?

McDonald's is located at 4422 West Commerce Street, San Antonio, TX 78237.

What is the phone number of McDonald's?

You can call McDonald's at (210) 438-5020.

Does McDonald's offer delivery or takeout?

Delivery is not listed for McDonald's, and takeout is available. Listed service options: takeout, drive-through, and dine-in.